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series s sensor chip prisma  (Cytiva Europe)


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    Structured Review

    Cytiva Europe series s sensor chip prisma
    Series S Sensor Chip Prisma, supplied by Cytiva Europe, used in various techniques. Bioz Stars score: 92/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/series+s+sensor+chip+prisma/Biacore+Series+S+Sensor+Chip+PrismA/pmc11044105__ac3c05607_si_001-4-22-27
    Average 92 stars, based on 2 article reviews
    series s sensor chip prisma - by Bioz Stars, 2026-11
    92/100 stars

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    Related Articles

    other:

    Article Title: Overcoming Lot-to-Lot Variability in Protein Activity Using Epitope-Specific Calibration-Free Concentration Analysis
    Article Snippet: Series S Sensor Chip CM5 (Cytiva BR100530), Series S Sensor Chip ProteinG (Cytiva 29179315), Series S Sensor Chip ProteinA (Cytiva 29127556) and Series S Sensor Chip PrismA (Cytiva 29650263) were used in this work.



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    92
    Cytiva Europe series s sensor chip prisma
    Series S Sensor Chip Prisma, supplied by Cytiva Europe, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/series+s+sensor+chip+prisma/Biacore+Series+S+Sensor+Chip+PrismA/pmc11044105__ac3c05607_si_001-4-22-27
    Average 92 stars, based on 1 article reviews
    series s sensor chip prisma - by Bioz Stars, 2026-11
    92/100 stars
      Buy from Supplier

    92
    Cytiva Europe series s prisma
    Fig. 1. Dynamic binding capacity (DBC) at 10% breakthrough. A) Comparison between MabSelect <t>PrismA</t> (dashed line) and Fibro PrismA (solid line) with log residence time. The residence time for Fibro™ PrismA was < 1 min and for MabSelect™ PrismA 4–5 min. B) Fibro PrismA DBC against residence time fitted by a two- parameter power function (dashed line). IgG1(•); IgG4–1 (∎); IgG4–2 (▴); IgG4–3(▾) and trivalent Fc (◆).
    Series S Prisma, supplied by Cytiva Europe, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/series+s+sensor+chip+prisma/Biacore+Series+S+Sensor+Chip+PrismA/10__1016_slash_j__bej__2023__109141-69-2-12
    Average 92 stars, based on 1 article reviews
    series s prisma - by Bioz Stars, 2026-11
    92/100 stars
      Buy from Supplier

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    Fig. 1. Dynamic binding capacity (DBC) at 10% breakthrough. A) Comparison between MabSelect PrismA (dashed line) and Fibro PrismA (solid line) with log residence time. The residence time for Fibro™ PrismA was < 1 min and for MabSelect™ PrismA 4–5 min. B) Fibro PrismA DBC against residence time fitted by a two- parameter power function (dashed line). IgG1(•); IgG4–1 (∎); IgG4–2 (▴); IgG4–3(▾) and trivalent Fc (◆).

    Journal: Biochemical Engineering Journal

    Article Title: Economic optimization of antibody capture through Protein A affinity nanofiber chromatography

    doi: 10.1016/j.bej.2023.109141

    Figure Lengend Snippet: Fig. 1. Dynamic binding capacity (DBC) at 10% breakthrough. A) Comparison between MabSelect PrismA (dashed line) and Fibro PrismA (solid line) with log residence time. The residence time for Fibro™ PrismA was < 1 min and for MabSelect™ PrismA 4–5 min. B) Fibro PrismA DBC against residence time fitted by a two- parameter power function (dashed line). IgG1(•); IgG4–1 (∎); IgG4–2 (▴); IgG4–3(▾) and trivalent Fc (◆).

    Article Snippet: The chip, Series S PrismA (Catalogue no. 29650264) was kindly provided by Cytiva.

    Techniques: Binding Assay, Comparison

    Fig. 2. Binding signal between different concentrations of proteins and PrismA ligands. A) Illustration of the SPR technique to determine static binding capacity. B) Experimental data and the fit to a Langmuir isotherm for binding signal against protein concentration. C) Error margins of parameter Qmax for each mAb. D) Error margins of parameter keq for each mAb.

    Journal: Biochemical Engineering Journal

    Article Title: Economic optimization of antibody capture through Protein A affinity nanofiber chromatography

    doi: 10.1016/j.bej.2023.109141

    Figure Lengend Snippet: Fig. 2. Binding signal between different concentrations of proteins and PrismA ligands. A) Illustration of the SPR technique to determine static binding capacity. B) Experimental data and the fit to a Langmuir isotherm for binding signal against protein concentration. C) Error margins of parameter Qmax for each mAb. D) Error margins of parameter keq for each mAb.

    Article Snippet: The chip, Series S PrismA (Catalogue no. 29650264) was kindly provided by Cytiva.

    Techniques: Binding Assay, Protein Concentration

    Fig. 4. Protein impurity clearance by MabSelect PrismA at 0.25 CV min-1 (∎) and Fibro PrismA at 40 MV min-1(•) as a function of the load density. Aggregates reduction is shown on the left hand side for IgG1, IgG4–3 and Trivalent Fc; while host cell protein (HCP) reduction is on the right hand side for the same proteins.

    Journal: Biochemical Engineering Journal

    Article Title: Economic optimization of antibody capture through Protein A affinity nanofiber chromatography

    doi: 10.1016/j.bej.2023.109141

    Figure Lengend Snippet: Fig. 4. Protein impurity clearance by MabSelect PrismA at 0.25 CV min-1 (∎) and Fibro PrismA at 40 MV min-1(•) as a function of the load density. Aggregates reduction is shown on the left hand side for IgG1, IgG4–3 and Trivalent Fc; while host cell protein (HCP) reduction is on the right hand side for the same proteins.

    Article Snippet: The chip, Series S PrismA (Catalogue no. 29650264) was kindly provided by Cytiva.

    Techniques:

    Fig. 5. Comparison of chromatograms for different elution volumes (10 MV and 15 MV) with HiTrap (0.4 mL) and HiScreen (3.75 mL) Fibro™ PrismA devices using IgG4–3 as the model. A) Whole chromatograms starting from sample loading; B) Elution profile. HiTrap Fibro PrismA and HiScreen Fibro PrismA were operated using ¨Akta Pure 25 and ¨Akta Pure 150, respectively.

    Journal: Biochemical Engineering Journal

    Article Title: Economic optimization of antibody capture through Protein A affinity nanofiber chromatography

    doi: 10.1016/j.bej.2023.109141

    Figure Lengend Snippet: Fig. 5. Comparison of chromatograms for different elution volumes (10 MV and 15 MV) with HiTrap (0.4 mL) and HiScreen (3.75 mL) Fibro™ PrismA devices using IgG4–3 as the model. A) Whole chromatograms starting from sample loading; B) Elution profile. HiTrap Fibro PrismA and HiScreen Fibro PrismA were operated using ¨Akta Pure 25 and ¨Akta Pure 150, respectively.

    Article Snippet: The chip, Series S PrismA (Catalogue no. 29650264) was kindly provided by Cytiva.

    Techniques: Comparison

    Fig. 6. Overlay of 200 cycles of IgG4–3 capture on Fibro PrismA for: A) Chromatograms; B) Delta pressure drop; C) Eluate peak width at half height; D) Peak height; E) Eluate volume; and F) Protein recovery.

    Journal: Biochemical Engineering Journal

    Article Title: Economic optimization of antibody capture through Protein A affinity nanofiber chromatography

    doi: 10.1016/j.bej.2023.109141

    Figure Lengend Snippet: Fig. 6. Overlay of 200 cycles of IgG4–3 capture on Fibro PrismA for: A) Chromatograms; B) Delta pressure drop; C) Eluate peak width at half height; D) Peak height; E) Eluate volume; and F) Protein recovery.

    Article Snippet: The chip, Series S PrismA (Catalogue no. 29650264) was kindly provided by Cytiva.

    Techniques:

    Fig. 7. Eluate quality over 200 cycles of IgG4–3 capture on Fibro PrismA. A) Aggregate reduction; B) Log HCP reduction; C) Intensity Average Particle size; and D) Protein A ligand leakage level.

    Journal: Biochemical Engineering Journal

    Article Title: Economic optimization of antibody capture through Protein A affinity nanofiber chromatography

    doi: 10.1016/j.bej.2023.109141

    Figure Lengend Snippet: Fig. 7. Eluate quality over 200 cycles of IgG4–3 capture on Fibro PrismA. A) Aggregate reduction; B) Log HCP reduction; C) Intensity Average Particle size; and D) Protein A ligand leakage level.

    Article Snippet: The chip, Series S PrismA (Catalogue no. 29650264) was kindly provided by Cytiva.

    Techniques:

    Fig. 9. Cost comparison between MabSelect PrismA and Fibro PrismA at manufacturing scale (2000 L). A) Total cost comparison for a single batch. Cost per gram mAb processed for up to 20 harvests at a manufacturing scale for B) A new membrane device is replaced every harvest; and C) The membrane device is replaced every 4 harvests (200 cycles).

    Journal: Biochemical Engineering Journal

    Article Title: Economic optimization of antibody capture through Protein A affinity nanofiber chromatography

    doi: 10.1016/j.bej.2023.109141

    Figure Lengend Snippet: Fig. 9. Cost comparison between MabSelect PrismA and Fibro PrismA at manufacturing scale (2000 L). A) Total cost comparison for a single batch. Cost per gram mAb processed for up to 20 harvests at a manufacturing scale for B) A new membrane device is replaced every harvest; and C) The membrane device is replaced every 4 harvests (200 cycles).

    Article Snippet: The chip, Series S PrismA (Catalogue no. 29650264) was kindly provided by Cytiva.

    Techniques: Comparison, Membrane

    Fig. 8. Helium ion microscopy analysis of Fibro PrismA before and after 200 cycles. A), B) Unused Fibro PrismA. C), D) Outlet region of the Fibro PrismA after 200 cycles at two different resolutions. The red circles showed polymer beads of fibers resulting from the electrospinning process.

    Journal: Biochemical Engineering Journal

    Article Title: Economic optimization of antibody capture through Protein A affinity nanofiber chromatography

    doi: 10.1016/j.bej.2023.109141

    Figure Lengend Snippet: Fig. 8. Helium ion microscopy analysis of Fibro PrismA before and after 200 cycles. A), B) Unused Fibro PrismA. C), D) Outlet region of the Fibro PrismA after 200 cycles at two different resolutions. The red circles showed polymer beads of fibers resulting from the electrospinning process.

    Article Snippet: The chip, Series S PrismA (Catalogue no. 29650264) was kindly provided by Cytiva.

    Techniques: Microscopy, Polymer

    Fig. 10. Cost comparison between MabSelect PrismA and Fibro PrismA at A) Pilot scale (200 L) and B) Clinical Scale (500 L).

    Journal: Biochemical Engineering Journal

    Article Title: Economic optimization of antibody capture through Protein A affinity nanofiber chromatography

    doi: 10.1016/j.bej.2023.109141

    Figure Lengend Snippet: Fig. 10. Cost comparison between MabSelect PrismA and Fibro PrismA at A) Pilot scale (200 L) and B) Clinical Scale (500 L).

    Article Snippet: The chip, Series S PrismA (Catalogue no. 29650264) was kindly provided by Cytiva.

    Techniques: Comparison